Trasylol Kidney Failure Study : Twofold Higher Risk for Heart Surgery Patients
The American Journal of Nephrology published a study on February 8, 2008 regarding Trasylol and kidney failure. Prior to being withdrawn from the marketplace Aprotinin was marketed as “Trasylol” by the drug company Bayer. This is the first Trasylol study to evaluate the effect of the drug on urinary NGAL (neutrophil gelatinase-associated lipocalin). Urinary NGAL increases significantly after kidney damage.
In this observational study involving 369 patients undergoing heart surgery, they were either given aprotinin or aminocraproic acid during surgery. 205 patients received aprotinin and 164 received aminocaproic acid. The study revealed that the patients who were given the medication aprotinin (Trasylol) during their surgery had a twofold higher risk of developing kidney failure compared to the patient group receiving aminocaproic acid. 25% of the patients receiving aprotinin (51 of the 205 patients) developed kidney failure. The outcome of this study confirm the results of Dr. Mangano’s earlier Trasylol study which revealed that patients who received the aprotinin had around a 50 percent increased risk of dying.
Study: Increased Incidence of Acute Kidney Injury with Aprotinin Use during Cardiac Surgery Detected with Urinary NGAL
Am J Nephrol 2008;28:576-582
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Trasylol Aprotinin Side Effects Study
Another study reveals an increased risk of serious Trasylol side effects leading to a higher mortality rate in aprotinin bypass patients. A recent study published in The New England Journal of Medicine on February 21, 2008 shows an increased risk of death for patients receiving aprotinin (Trasylol) during coronary-artery bypass grafting [...]
Trasylol Heart Surgery Drug Information
What is aprotinin injection?
APROTININ (Trasylol) is a drug that affects the way blood clots. It was given to heart surgery patients during bypass procedures. Aprotinin was mainly used during repeat coronary artery bypass surgery to reduce the amount of bleeding before and after surgery. Trasylol and other clotting medications help to [...]
An increasing number of studies have suggested Trasylol is a potentially dangerous drug and an expensive one. The cost per dose of Trasylol is $1,300. The generic drug Amicar is $11 per dose and the generic Cyklokapron is $44 per dose. According to the studies, neither of the generic drugs has been associated with an [...]
Patients and families nationwide have looked at filing a Trasylol lawsuit based on the often fatal side effects of the drug Trasylol. Currently no Trasylol class action suits have been filed by Fields Law Firm and claims are being made individually.
The lawsuits claim that Bayer, the drug’s manufacturer, was negligent in several ways including:
• marketing [...]
